Emx2 encodes for a transcription factor implicated in several aspects of cerebral cortex development, such as morphogenetic field specification, arealization, and lamination. Its overexpression in cortico-cerebral precursors may promote stem cells self-renewal, inhibits their gliogenic commitment, protects neuronal progenitors and stimulates their differentiation, all activities of paramount relevance for purposes of genepromoted brain repair.

Promotion of cortico-cerebral precursors expansion by artificial miRNAs against the Emx2 locus / Diodato, Assunta. - (2011 Feb 16).

Promotion of cortico-cerebral precursors expansion by artificial miRNAs against the Emx2 locus

Diodato, Assunta
2011-02-16

Abstract

Emx2 encodes for a transcription factor implicated in several aspects of cerebral cortex development, such as morphogenetic field specification, arealization, and lamination. Its overexpression in cortico-cerebral precursors may promote stem cells self-renewal, inhibits their gliogenic commitment, protects neuronal progenitors and stimulates their differentiation, all activities of paramount relevance for purposes of genepromoted brain repair.
16-feb-2011
Mallamaci, Antonio
Diodato, Assunta
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11767/4116
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