The calcium-activated chloride channel TMEM16A is involved in several physiological processes and is an important pharmacological target. Dinsdale and colleagues recently unveiled several residues in the outer pore region that constitute a critical site for the design of drugs that modulate TMEM16A channels.

Paving the way for designing drugs targeting TMEM16A / Pifferi, S.; Menini, A.. - In: TRENDS IN PHARMACOLOGICAL SCIENCES. - ISSN 0165-6147. - 42:12(2021), pp. 979-980. [10.1016/j.tips.2021.10.005]

Paving the way for designing drugs targeting TMEM16A

Menini, A.
2021-01-01

Abstract

The calcium-activated chloride channel TMEM16A is involved in several physiological processes and is an important pharmacological target. Dinsdale and colleagues recently unveiled several residues in the outer pore region that constitute a critical site for the design of drugs that modulate TMEM16A channels.
2021
10.1016/j.tips.2021.10.005
Pifferi, S.; Menini, A.
File in questo prodotto:
File Dimensione Formato  
2021 PIfferi_TrendsPharmacol.pdf

non disponibili

Descrizione: pdf editoriale
Tipologia: Versione Editoriale (PDF)
Licenza: Non specificato
Dimensione 465.15 kB
Formato Adobe PDF
465.15 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11767/126689
Citazioni
  • ???jsp.display-item.citation.pmc??? 1
  • Scopus 1
  • ???jsp.display-item.citation.isi??? 1
social impact