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Distinct tau fibril types and their role in prion diseases

Neurodegenerative diseases are often characterized by the co-deposition of different amyloidogenic proteins, normally defining distinct proteinopathies. An interesting example is represented by prion diseases, in which the presence of PrPSc plaques is often accompanied by aggregates of the tau protein, normally implicated in another class of diseases called tauopathies. How this copresence of amyloidogenic proteins can influence the progression of prion disease is still a matter of debate. ...

A study of rat perceptual sensitivity to multipoint correlations and their representation in the visual cortex

Efficient processing of sensory data requires adapting the neuronal encoding strategy to the statistics of natural stimuli. Previously, Multiple studies showed that local multipoint correlation patterns that are most variable in natural images are also the most perceptually salient for human observers, in a way that is compatible with the efficient coding principle. Understanding the neuronal mechanisms underlying such adaptation to image statistics will require performing invasive experiment...

Constraining modifications of black hole perturbation potentials near the light ring with quasinormal modes

In modified theories of gravity, the potentials appearing in the Schrödinger-like equations that describe perturbations of nonrotating black holes are also modified. In this paper we ask: can these modifications be constrained with high-precision gravitational-wave measurements of the black hole's quasinormal mode frequencies? We expand the modifications in a small perturbative parameter regulating the deviation from the general-relativistic potential, and in powers of M/r. We compute the qua...

Metabolic reprogramming and membrane glycan remodeling as potential drivers of zebrafish heart regeneration

The ability of the zebrafish heart to regenerate following injury makes it a valuable model to deduce why this capability in mammals is limited to early neonatal stages. Although metabolic reprogramming and glycosylation remodeling have emerged as key aspects in many biological processes, how they may trigger a cardiac regenerative response in zebrafish is still a crucial question. Here, by using an up-to-date panel of transcriptomic, proteomic and glycomic approaches, we identify a metabolic...

Charge and heat transport in ionic conductors

Transport coefficients relate the off-equilibrium flow of locally conserved quantities, such as charge, energy, and momentum, to gradients of intensive thermodynamic variables in the linear regime. Despite their mathematical formalization dating back to the middle of the last century, when Green and Kubo developed linear response theory, some conceptual subtleties were only recently understood through the formulation of the gauge-invariance and convective-invariance principles. In a nutshell,...

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Tipologia
  • 1 Article8980
  • 8 Thesis2165
  • 4 Conference object704
  • 2 Book part299
  • 3 Book50
  • 5 Other25
  • 6 Patent20
  • 7 Trusteeship14
Autore
  • Legname, Giuseppe328
  • Baccigalupi, Carlo319
  • Danese, Luigi315
  • Bressan, Alessandro225
  • Viel, Matteo221
  • Baroni, Stefano213
  • Calabrese, Pasquale206
  • Tosatti, Erio200
  • De Zotti, Gianfranco196
  • Liberati, Stefano193
Data di pubblicazione
  • In corso di stampa18
  • 2020 - 20231244
  • 2010 - 20195179
  • 2000 - 20093449
  • 1990 - 19991663
  • 1980 - 1989615
  • 1970 - 197975
  • 1962 - 196914
Editore
  • SISSA2140
  • Springer101
  • World Scientific45
  • Elsevier21
  • Cambridge University Press19
  • Oxford University Press18
  • Springer International Publishing14
  • American Institute of Physics12
  • IEEE12
  • Sissa Medialab Srl12
Rivista
  • MONTHLY NOTICES OF THE ROYAL ASTR...410
  • JOURNAL OF HIGH ENERGY PHYSICS363
  • ASTRONOMY & ASTROPHYSICS362
  • PHYSICAL REVIEW. B, CONDENSED MAT...335
  • PHYSICAL REVIEW LETTERS334
  • THE ASTROPHYSICAL JOURNAL218
  • PHYSICAL REVIEW D, PARTICLES, FIE...193
  • JOURNAL OF COSMOLOGY AND ASTROPAR...191
  • NUCLEAR PHYSICS. B190
  • PHYSICS LETTERS. SECTION B177
Serie
  • AIP CONFERENCE PROCEEDINGS17
  • LECTURE NOTES IN PHYSICS14
  • LECTURE NOTES IN COMPUTATIONAL SC...10
  • PROCEEDINGS OF SPIE, THE INTERNAT...10
  • ASTRONOMICAL SOCIETY OF THE PACIF...7
  • LECTURE NOTES IN COMPUTER SCIENCE7
  • PROCEEDINGS OF THE IEEE CONFERENC...7
  • LECTURE NOTES IN MATHEMATICS6
  • SPRINGER INDAM SERIES6
  • CISM INTERNATIONAL CENTRE FOR MEC...5
Settore disciplinare
  • Settore FIS/05 - Astronomia e Ast...1794
  • Settore FIS/03 - Fisica della Mat...1532
  • Settore FIS/02 - Fisica Teorica, ...1346
  • Settore MAT/05 - Analisi Matematica595
  • Settore BIO/09 - Fisiologia466
  • Settore MAT/07 - Fisica Matematica458
  • Settore M-PSI/02 - Psicobiologia ...350
  • Settore MAT/08 - Analisi Numerica225
  • Settore MAT/03 - Geometria224
  • Settore BIO/10 - Biochimica115
Keyword
  • Cosmic background radiation87
  • Astronomy and Astrophysics72
  • Animals66
  • dark matter66
  • Humans65
  • Physics and Astronomy (all)64
  • Cosmology: observations62
  • galaxies: evolution61
  • Space and Planetary Science59
  • Condensed Matter Physics58
Lingua
  • eng11119
  • ita373
  • Inglese148
  • fre10
  • Italiano7
  • und5
  • rus2
  • English1
  • ger1
  • spa1
Accesso al fulltext
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  • open4388
  • reserved3050
  • partially open200
  • embargoed53