PROBLEM TO BE SOLVED: To provide a functional nucleic acid molecule directly improving the efficiency of protein synthesis.SOLUTION: According to the present invention, there are provided (a) a functional nucleic acid molecule comprising: a target determining sequence containing an antisense sequence against a target sequence in RNA encoding a protein, which is an object of improving the efficiency of protein synthesis; and a regulatory sequence having an activity of improving the efficiency of protein synthesis, and (b) the use of such a functional nucleic acid molecule. In the functional nucleic acid molecule, the regulatory sequence is a sequence derived from SINE-B2.

Functional nucleic acid molecule and use thereof / Gustincich, S.; Carrieri, C.; Zucchelli, S.; Carninci, P.; Forrest, A. R.. - (2011 Mar 30).

Functional nucleic acid molecule and use thereof

Gustincich, S.;
2011-03-30

Abstract

PROBLEM TO BE SOLVED: To provide a functional nucleic acid molecule directly improving the efficiency of protein synthesis.SOLUTION: According to the present invention, there are provided (a) a functional nucleic acid molecule comprising: a target determining sequence containing an antisense sequence against a target sequence in RNA encoding a protein, which is an object of improving the efficiency of protein synthesis; and a regulatory sequence having an activity of improving the efficiency of protein synthesis, and (b) the use of such a functional nucleic acid molecule. In the functional nucleic acid molecule, the regulatory sequence is a sequence derived from SINE-B2.
US201161469399P 20110330
Gustincich, S.; Carrieri, C.; Zucchelli, S.; Carninci, P.; Forrest, A. R.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/20.500.11767/15735
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