PROBLEM TO BE SOLVED: To provide a functional nucleic acid molecule directly improving the efficiency of protein synthesis.SOLUTION: According to the present invention, there are provided (a) a functional nucleic acid molecule comprising: a target determining sequence containing an antisense sequence against a target sequence in RNA encoding a protein, which is an object of improving the efficiency of protein synthesis; and a regulatory sequence having an activity of improving the efficiency of protein synthesis, and (b) the use of such a functional nucleic acid molecule. In the functional nucleic acid molecule, the regulatory sequence is a sequence derived from SINE-B2.
|Titolo:||Functional nucleic acid molecule and use thereof|
|Autori:||Gustincich, S.; Carrieri, C.; Zucchelli, S.; Carninci, P.; Forrest, A. R.|
|Data di deposito:||2011-03-30|
|Numero di deposito:||US201161469399P 20110330|
|Appare nelle tipologie:||6.1 Patent|