The present invention provides ligands capable of binding to prion protein, such as anti-prion protein antibodies and antigen-binding fragment thereof, for the prevention and/or treatment of synucleinopathies, such as Parkinson's disease. The present invention also provides pharmaceutical compositions comprising such ligands and methods for treating synucleinopathies or for reducing the uptake of ±-synuclein fibrils.

Ligands binding to prion protein for use in the treatment of synucleinopathies / Legname, G.. - (2017 May 23).

Ligands binding to prion protein for use in the treatment of synucleinopathies

Legname, G.
2017

Abstract

The present invention provides ligands capable of binding to prion protein, such as anti-prion protein antibodies and antigen-binding fragment thereof, for the prevention and/or treatment of synucleinopathies, such as Parkinson's disease. The present invention also provides pharmaceutical compositions comprising such ligands and methods for treating synucleinopathies or for reducing the uptake of ±-synuclein fibrils.
EP20170425051 20170523
Legname, G.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11767/88885
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