The present invention provides ligands capable of binding to prion protein, such as anti-prion protein antibodies and antigen-binding fragment thereof, for the prevention and/or treatment of synucleinopathies, such as Parkinson's disease. The present invention also provides pharmaceutical compositions comprising such ligands and methods for treating synucleinopathies or for reducing the uptake of ±-synuclein fibrils.

Ligands binding to prion protein for use in the treatment of synucleinopathies / Legname, G.. - (2017 May 23).

Ligands binding to prion protein for use in the treatment of synucleinopathies

Legname, G.
2017-05-23

Abstract

The present invention provides ligands capable of binding to prion protein, such as anti-prion protein antibodies and antigen-binding fragment thereof, for the prevention and/or treatment of synucleinopathies, such as Parkinson's disease. The present invention also provides pharmaceutical compositions comprising such ligands and methods for treating synucleinopathies or for reducing the uptake of ±-synuclein fibrils.
EP20170425051 20170523
Legname, G.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/20.500.11767/88885
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