In this study, we analyze the effectiveness of measures aimed at finding and isolating infected individuals to contain epidemics like COVID-19, as the suppression induced over the effective reproduction number. We develop a mathematical model to compute the relative suppression of the effective reproduction number of an epidemic that such measures produce. This outcome is expressed as a function of a small set of parameters that describe the main features of the epidemic and summarize the effectiveness of the isolation measures. In particular, we focus on the impact when a fraction of the population uses a mobile application for epidemic control. Finally, we apply the model to COVID-19, providing several computations as examples, and a link to a public repository to run custom calculations. These computations display in a quantitative manner the importance of recognizing infected individuals from symptoms and contact-tracing information, and isolating them as early as possible. The computations also assess the impact of each variable on the mitigation of the epidemic.

Effectiveness of isolation measures with app support to contain COVID-19 epidemics: a parametric approach / Maiorana, Andrea; Meneghelli, Marco; Resnati, Mario. - In: JOURNAL OF MATHEMATICAL BIOLOGY. - ISSN 0303-6812. - 83:5(2021). [10.1007/s00285-021-01660-9]

Effectiveness of isolation measures with app support to contain COVID-19 epidemics: a parametric approach

Maiorana, Andrea;
2021-01-01

Abstract

In this study, we analyze the effectiveness of measures aimed at finding and isolating infected individuals to contain epidemics like COVID-19, as the suppression induced over the effective reproduction number. We develop a mathematical model to compute the relative suppression of the effective reproduction number of an epidemic that such measures produce. This outcome is expressed as a function of a small set of parameters that describe the main features of the epidemic and summarize the effectiveness of the isolation measures. In particular, we focus on the impact when a fraction of the population uses a mobile application for epidemic control. Finally, we apply the model to COVID-19, providing several computations as examples, and a link to a public repository to run custom calculations. These computations display in a quantitative manner the importance of recognizing infected individuals from symptoms and contact-tracing information, and isolating them as early as possible. The computations also assess the impact of each variable on the mitigation of the epidemic.
2021
83
5
43
10.1007/s00285-021-01660-9
https://arxiv.org/abs/2011.02349
Maiorana, Andrea; Meneghelli, Marco; Resnati, Mario
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11767/142610
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