Modeling noisy oscillations of active systems is one of the current challenges in physics and biology. Because the physical mechanisms of such processes are often difficult to identify, we propose a linear stochastic model driven by a non-Markovian bistable noise that is capable of generating self-sustained periodic oscillation. We derive analytical predictions for most relevant dynamical and thermodynamic properties of the model. This minimal model turns out to describe accurately bistablelike oscillatory motion of hair bundles in bullfrog sacculus, extracted from experimental data. Based on and in agreement with these data, we estimate the power required to sustain such active oscillations to be of the order of 100 kBT per oscillation cycle.

Modeling Active Non-Markovian Oscillations / Tucci, G.; Roldán, E.; Gambassi, A.; Belousov, R.; Berger, F.; Alonso, R. G.; Hudspeth, A. J.. - In: PHYSICAL REVIEW LETTERS. - ISSN 0031-9007. - 129:3(2022). [10.1103/PhysRevLett.129.030603]

Modeling Active Non-Markovian Oscillations

Tucci, G.;Gambassi, A.;
2022-01-01

Abstract

Modeling noisy oscillations of active systems is one of the current challenges in physics and biology. Because the physical mechanisms of such processes are often difficult to identify, we propose a linear stochastic model driven by a non-Markovian bistable noise that is capable of generating self-sustained periodic oscillation. We derive analytical predictions for most relevant dynamical and thermodynamic properties of the model. This minimal model turns out to describe accurately bistablelike oscillatory motion of hair bundles in bullfrog sacculus, extracted from experimental data. Based on and in agreement with these data, we estimate the power required to sustain such active oscillations to be of the order of 100 kBT per oscillation cycle.
2022
129
3
030603
10.1103/PhysRevLett.129.030603
https://arxiv.org/abs/2201.12171
Tucci, G.; Roldán, E.; Gambassi, A.; Belousov, R.; Berger, F.; Alonso, R. G.; Hudspeth, A. J.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11767/131791
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