Emx2 encodes for a transcription factor implicated in several aspects of cerebral cortex development, such as morphogenetic field specification, arealization, and lamination. Its overexpression in cortico-cerebral precursors may promote stem cells self-renewal, inhibits their gliogenic commitment, protects neuronal progenitors and stimulates their differentiation, all activities of paramount relevance for purposes of genepromoted brain repair.
Promotion of cortico-cerebral precursors expansion by artificial miRNAs against the Emx2 locus / Diodato, Assunta. - (2011 Feb 16).
Promotion of cortico-cerebral precursors expansion by artificial miRNAs against the Emx2 locus
Diodato, Assunta
2011-02-16
Abstract
Emx2 encodes for a transcription factor implicated in several aspects of cerebral cortex development, such as morphogenetic field specification, arealization, and lamination. Its overexpression in cortico-cerebral precursors may promote stem cells self-renewal, inhibits their gliogenic commitment, protects neuronal progenitors and stimulates their differentiation, all activities of paramount relevance for purposes of genepromoted brain repair.File in questo prodotto:
| File | Dimensione | Formato | |
|---|---|---|---|
|
1963_4946_PhD Thesis_Diodato A.pdf
accesso aperto
Tipologia:
Tesi
Licenza:
Non specificato
Dimensione
5.74 MB
Formato
Adobe PDF
|
5.74 MB | Adobe PDF | Visualizza/Apri |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
