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Advanced Perspectives in Non-Equilibrium Quantum Dynamics

Spatial organization of DNA across scales: a Bayesian inference and information-theoretic approach

Spatial organization plays a fundamental role in many biological processes, from the folding of chromatin within the nucleus and the patterns of gene expression levels that guide cell fate decisions within an embryo during development. Understanding how the spatial arrangement of genetic material is connected to biochemical processes and cellular function is crucial for deciphering mechanisms of gene expression and development. This thesis presents an investigation across multiple scales of t...

CFD-DEM Simulation of the Deposition of Pharmaceutical Aerosols in Human Airways

Recent advances in the characterization of the human respiratory system and in multi-phase flow dynamics in complex geometries have led numerical simulations to play an expanding role for exploring aerosol deposition mechanisms in the lungs. However, the development of an efficient numerical and mathematical description is far from unique, and determining which aspects of the modeling are critical and which details are essentially irrelevant is indeed a difficult task. With the aim of address...

Dust in hydrodynamic and semi-analytic galaxy evolution simulations

Dust grains are fundamental components of the galaxies of our Universe, affecting both the physical processes of galaxy evolution and their observability. Therefore, incorporating dust physics into galaxy evolution simulations is essential. This Thesis investigates various aspects of dust within galaxy evolution using a state-of-the-art dust model integrated into two commonly adopted tools: hydrodynamic simulations and semi-analytic models (SAMs). The dust model includes both stellar producti...