Legname, Giuseppe
 Distribuzione geografica
Continente #
EU - Europa 21.052
NA - Nord America 15.690
AS - Asia 7.623
SA - Sud America 853
Continente sconosciuto - Info sul continente non disponibili 113
AF - Africa 60
OC - Oceania 25
Totale 45.416
Nazione #
US - Stati Uniti d'America 15.052
RU - Federazione Russa 7.943
IT - Italia 3.011
CN - Cina 2.756
SE - Svezia 2.736
IE - Irlanda 2.392
SG - Singapore 2.344
UA - Ucraina 1.440
TR - Turchia 1.125
HK - Hong Kong 958
DE - Germania 919
GB - Regno Unito 815
BR - Brasile 773
CA - Canada 610
FI - Finlandia 518
FR - Francia 304
LU - Lussemburgo 232
AT - Austria 142
VN - Vietnam 141
CH - Svizzera 128
EU - Europa 108
NL - Olanda 103
BE - Belgio 98
GR - Grecia 60
LB - Libano 52
RO - Romania 42
UZ - Uzbekistan 39
PL - Polonia 33
ES - Italia 27
IN - India 27
CZ - Repubblica Ceca 26
AR - Argentina 23
JP - Giappone 22
KR - Corea 22
BD - Bangladesh 19
PT - Portogallo 16
IQ - Iraq 14
NZ - Nuova Zelanda 14
PK - Pakistan 14
EC - Ecuador 13
MX - Messico 13
MA - Marocco 12
ZA - Sudafrica 12
AU - Australia 11
IL - Israele 11
CO - Colombia 10
MD - Moldavia 10
VE - Venezuela 10
AE - Emirati Arabi Uniti 9
KE - Kenya 9
AZ - Azerbaigian 8
TH - Thailandia 8
AL - Albania 7
CL - Cile 7
DK - Danimarca 7
PE - Perù 7
EG - Egitto 6
NP - Nepal 6
PS - Palestinian Territory 6
DO - Repubblica Dominicana 5
DZ - Algeria 5
HR - Croazia 5
HU - Ungheria 5
ID - Indonesia 5
LK - Sri Lanka 5
SA - Arabia Saudita 5
SK - Slovacchia (Repubblica Slovacca) 5
JO - Giordania 4
LT - Lituania 4
PY - Paraguay 4
SC - Seychelles 4
SI - Slovenia 4
TN - Tunisia 4
TW - Taiwan 4
UY - Uruguay 4
AM - Armenia 3
BG - Bulgaria 3
CR - Costa Rica 3
NO - Norvegia 3
PA - Panama 3
TZ - Tanzania 3
A2 - ???statistics.table.value.countryCode.A2??? 2
BA - Bosnia-Erzegovina 2
BY - Bielorussia 2
IM - Isola di Man 2
IR - Iran 2
IS - Islanda 2
KG - Kirghizistan 2
KZ - Kazakistan 2
LV - Lettonia 2
MN - Mongolia 2
NG - Nigeria 2
OM - Oman 2
PH - Filippine 2
RS - Serbia 2
XK - ???statistics.table.value.countryCode.XK??? 2
A1 - Anonimo 1
AO - Angola 1
BO - Bolivia 1
BT - Bhutan 1
Totale 45.404
Città #
Chandler 2.689
Dublin 2.390
Jacksonville 1.780
Scuola 1.668
Ann Arbor 1.211
Moscow 1.202
Hong Kong 948
Singapore 932
Wilmington 905
Boardman 871
New York 869
Ashburn 834
Izmir 792
Saint Petersburg 729
Nanjing 632
Toronto 567
Woodbridge 511
Princeton 330
Shanghai 324
Dearborn 320
Istanbul 302
Pisa 300
Houston 275
Nanchang 250
Helsinki 247
Beijing 239
Ogden 236
Santa Clara 198
Council Bluffs 175
The Dalles 166
Milan 146
Brooklyn 134
Luxembourg 131
Dong Ket 130
Kunming 124
Trieste 110
Sauris 104
Falls Church 97
Brussels 96
Tianjin 95
Dudelange 90
Seattle 79
Vienna 78
Shenyang 77
Hebei 76
Changsha 69
Nuremberg 68
Hangzhou 65
São Paulo 60
Jiaxing 57
Verona 56
Lausanne 54
Changchun 42
Washington 42
Berlin 41
Yubileyny 41
Rome 39
Orange 38
Frankfurt Am Main 37
Guangzhou 37
Strasbourg 37
Lanzhou 34
Dongguan 33
Hanover 32
Timisoara 31
Las Vegas 29
Ningbo 28
Redwood City 28
Los Angeles 27
Rio de Janeiro 26
Zhengzhou 25
Jinan 24
Torino 24
Frankfurt am Main 22
Costa Mesa 21
Hefei 21
Belo Horizonte 19
Borås 19
Taizhou 19
Auburn Hills 18
Norwalk 17
Ottawa 17
Redmond 17
Assago 16
Düsseldorf 16
Udine 16
Bologna 15
Den Haag 15
Curitiba 14
Grafing 14
London 14
Shenzhen 13
Turin 13
Brasília 11
Chengdu 11
Munich 11
San Francisco 11
Southend 11
Baghdad 10
Boston 10
Totale 25.994
Nome #
Discrimination of MSA-P and MSA-C by RT-QuIC analysis of olfactory mucosa: the first assessment of assay reproducibility between two specialized laboratories 340
Brain aging: A Ianus-faced player between health and neurodegeneration 275
alpha-Synuclein Amyloids Hijack Prion Protein to Gain Cell Entry, Facilitate Cell-to-Cell Spreading and Block Prion Replication 231
Detection of prion seeding activity in the olfactory mucosa of patients with Fatal Familial Insomnia 229
The non-octarepeat copper binding site of the prion protein is a key regulator of prion conversion 228
Characterization of prion protein function by focal neurite stimulation 224
Synthetic mammalian prions 218
Differential overexpression of SERPINA3 in human prion diseases 213
Cellular prion protein: Role in excitotoxicity and in metal ions homeostasis 211
Prion protein and copper cooperatively protect neurons by modulating NMDA receptor through S-nitrosylation 209
Whole blood gene expression profiling in preclinical and clinical cattle infected with atypical bovine spongiform encephalopathy 209
Structural features of human prion protein variants revealed by NMR 208
Nanoparticelle di oro rivestite con polielettroliti e loro uso come medicamento per il trattamento di malattie neurodegenerative causate da aggregati proteici 208
Altered Brain Hemoglobin Gene Expression in the Frontal Cortex of Patients with Alzheimer’s and Acquired Creutzfeldt-Jakob’s Disease 206
Serpin inhibitors for the treatment of prion and prion-like diseases 203
Gene Expression Profiling of Prion-Infected Brains: a Novel Disease Signature for Neurodegeneration in Humans 200
Processo per la preparazione di proteine inibenti i ribosomi 198
Anti-prion activity generated by two soil compounds-Humic and fulvic acids 197
Synthetic prions with novel strain-specified properties 196
A new approach to follow a single extracellular vesicle-cell interaction using optical tweezers 196
Developmental prion protein expression in eutherian and methaterian mammalian central nervous system 196
Synthetic prions and other human neurodegenerative proteinopathies 195
The N Terminus of the Prion Protein Mediates Functional Interactions with the Neuronal Cell Adhesion Molecule (NCAM) Fibronectin Domain 193
Recent Advances of Biology and Medicinal Chemistry of Prion Protein and Prions: On the Road to Therapeutics 192
A structural characterization of recombinant mouse prion protein amyloid fibers 192
Early structural features in mammalian prion conformation conversion 189
Brain delivery of AVV9 expressing anti-PrP molecules delays prion disease onsite in mice 189
Hemoglobin mRNA changes in the frontal cortex of patients with neurodegenerative diseases 189
Nucleotide sequences coding for ribosome inactivating proteins 188
Preface 184
Gene expression profiling of brains from bovine spongiform encephalopathy (BSE)-infected cynomolgus macaques 183
The mechanisms of humic substances self-assembly with biological molecules: The case study of the prion protein 183
Humic substances underlies the odds of environmental TSEs transmission 181
The role of the prion protein in the internalization of α-synuclein amyloids 181
Structural Variations of Prion Proteins Caused by Mutations in Human Genome 180
Glia-to-neuron transfer of miRNAs via extracellular vesicles: a new mechanism underlying inflammation-induced synaptic alterations 180
Prion protein interaction with soil humic substances: environmental implications 179
Identification of novel fluorescent probes preventing PrPSc replication in prion diseases 179
NMR structure of the human prion protein with the pathological Q212P mutation: insights into inherited human prion diseases 179
Efficient RT-QuIC seeding activity for α-synuclein in olfactory mucosa samples of patients with Parkinson's disease and multiple system atrophy 179
Cloning and characterization of a gene, inducible by cytokines 178
Whole transcriptome analysis in brains from BSE-infected macaques 178
Measuring prions causing bovine spongiform encephalopathy or chronic wasting disease by immunoassays and transgenic mice 177
Defined α-synuclein prion-like molecular assemblies spreading in cell culture 176
NMR Structures of the Human Prion Protein with Pathological Mutations: Insights Into Molecular Basis of Prion Disease 176
A search for auxiliary proteins in prion replication 176
Synthetic prions: De novo prion-infected neuronal cell lines and the generation of diverse infectious materials 176
In Vitro Aggregation Assays for the Characterization of α-synuclein Prion-Like Properties 175
Effects of the pathological Q212P mutation on human prion protein non-octarepeat copper-binding site 173
Oriented immobilization of prion protein demonstrated via precise interfacial nanostructure measurements 171
Soil humic substances hinder the propagation of prions 171
Novel Approaches to Diagnosis and Therapy in Neurodegenerative Diseases 169
NMR structure of the human prion protein Q212P mutant 168
Conformational properties of intrinsically disordered proteins bound to the surface of silica nanoparticles 167
A Fluorescent Styrylquinoline with Combined Therapeutic and Diagnostic Activities against Alzheimer’s and Prion Diseases 166
NMR structure of the human prion protein with the pathological Q212P mutation reveals unique structural features 166
Prions 166
Copper-catalyzed oxidation of the recombinant SHa (29-231) prion protein 165
Humic substances and therapeutic uses thereof 164
A single point mutation, a way to prion disease? 164
Method of amplifying infectious proteins 164
Developmental role of the prion protein in the nervous system 163
The amino-terminal-fragment of human urokinase fused to the plant toxin saporin targets the recombinant fusion toxin to urokinase-receptor bearing-cells: is internalization mediated by the toxin? 163
AGFD 199 - Isolation and characterization of new anti-PrP monoclonal antibodies 163
Prion protein and aging 162
Nucleotide sequence coding for ribosome inactivating proteins 161
Induction of Protease-Resistant Prion Protein and alpha-synuclein Aggregation by Human alpha-synuclein Fibrils in Cultured Cells 161
Cloning and characterization of a gene, inducible by cytokines 161
Ligands binding to prion protein for use in the treatment of synucleinopathies 161
Nanobody-stabilize the crystal structure of full-length human PrP 160
Pin1 and neurodegeneration: a new player for prion disorders? 160
New insights into structural determinants of prion protein folding and stability 160
Methionine oxidation in α-synuclein inhibits its propensity for ordered secondary structure 160
Toward the molecular basis of inherited prion diseases: NMR structure of the human prion protein with V210I mutation 159
Anti-GM1 IgM antibodies in motor neuron disease (MND) and other neurological diseases 159
Effect of extracellular vesicles derived from distinct brain cells on A beta toxicity and assembly: focus on microglia derived vesicles 159
Structural determinants in prion protein folding and stability 158
In Absence of the Cellular Prion Protein, Alterations in Copper Metabolism and Copper-Dependent Oxidase Activity Affect Iron Distribution 158
Molecular pathogenesis of prion diseases 158
Antemortem Prion Diagnostics 157
Developmental influence of the cellular prion protein on the gene expression profile in mouse hippocampus 157
Nucleotide sequences coding for ribosome inactivating proteins 157
Dominant-negative effects in prion diseases: insights from molecular dynamics simulations on mouse prion protein chimeras 157
Altered molecular signaling in neuronal cell models of prion infection 156
De novo generation of mammalian prions 156
Humic substances and uses thereof in agro-environment 156
Gene expression profiling and therapeutic interventions in neurodegenerative diseases: a comprehensive study on potentiality and limits 156
Effects of the pathological Q212P mutation on human prion protein non-octarepeat copper binding site 156
Structural facets of disease-linked human prion protein mutants: A molecular dynamic study 156
Effects of tetrahydrocannabinol on melatonin secretion in man 154
A change in the conformation of prions accompanies the emergence of a new prion strain 154
Neurodevelopmental expression and localization of the cellular prion protein in the central nervous system of the mouse 152
Antagonistic cellular functions for prion protein and its paralog doppel. 152
Anti-CD30 immunotoxins with native and recombinant dianthin 30 152
Inferring prion partners from Gene-Networks 152
Opposite Structural Effects of Epigallocatechin-3-gallate and Dopamine Binding to α-Synuclein 151
Cytosolic localization of prion protein in neuronal cells in brain of mice 151
Design of ligands with a high affinity to the cellular form of the prion protein 150
Parallel synthesis, evaluation, and preliminary structure-activity relationship of 2,5-diamino-1,4-benzoquinones as a novel class of bivalent anti-prion compound 150
TDP-43 real-time quaking induced conversion reaction optimization and detection of seeding activity in CSF of amyotrophic lateral sclerosis and frontotemporal dementia patients 149
Totale 17.813
Categoria #
all - tutte 187.986
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 187.986


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020380 0 0 0 0 0 0 0 0 0 0 344 36
2020/20213.585 441 94 33 332 66 677 471 24 395 382 149 521
2021/20223.292 483 370 18 334 568 94 202 365 144 107 195 412
2022/20238.209 1.218 896 735 782 431 1.663 883 528 769 62 114 128
2023/20244.799 279 71 178 82 708 1.960 184 261 739 66 59 212
2024/202513.593 2.325 800 1.519 3.663 1.677 719 799 843 660 544 44 0
Totale 46.748