Legname, Giuseppe
 Distribuzione geografica
Continente #
EU - Europa 20.427
NA - Nord America 15.146
AS - Asia 5.871
Continente sconosciuto - Info sul continente non disponibili 111
SA - Sud America 60
OC - Oceania 23
AF - Africa 14
Totale 41.652
Nazione #
US - Stati Uniti d'America 14.546
RU - Federazione Russa 7.912
IT - Italia 2.886
SE - Svezia 2.734
CN - Cina 2.389
IE - Irlanda 2.385
SG - Singapore 1.557
UA - Ucraina 1.433
TR - Turchia 1.098
DE - Germania 829
GB - Regno Unito 804
CA - Canada 596
HK - Hong Kong 493
FI - Finlandia 488
FR - Francia 294
VN - Vietnam 140
CH - Svizzera 128
EU - Europa 108
BE - Belgio 93
AT - Austria 82
LU - Lussemburgo 79
GR - Grecia 60
LB - Libano 50
NL - Olanda 47
BR - Brasile 46
RO - Romania 40
PL - Polonia 31
UZ - Uzbekistan 30
ES - Italia 27
CZ - Repubblica Ceca 24
IN - India 22
KR - Corea 22
JP - Giappone 20
NZ - Nuova Zelanda 12
AU - Australia 11
MD - Moldavia 10
PT - Portogallo 10
IL - Israele 7
DK - Danimarca 5
HR - Croazia 5
ID - Indonesia 5
TH - Thailandia 5
CL - Cile 4
HU - Ungheria 4
PK - Pakistan 4
SI - Slovenia 4
TW - Taiwan 4
AE - Emirati Arabi Uniti 3
AR - Argentina 3
BD - Bangladesh 3
CO - Colombia 3
DZ - Algeria 3
LK - Sri Lanka 3
MX - Messico 3
NO - Norvegia 3
PS - Palestinian Territory 3
SA - Arabia Saudita 3
SK - Slovacchia (Repubblica Slovacca) 3
TZ - Tanzania 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AM - Armenia 2
BG - Bulgaria 2
KE - Kenya 2
KZ - Kazakistan 2
PH - Filippine 2
RS - Serbia 2
SC - Seychelles 2
A1 - Anonimo 1
AL - Albania 1
AZ - Azerbaigian 1
BT - Bhutan 1
CU - Cuba 1
EC - Ecuador 1
EG - Egitto 1
ET - Etiopia 1
FK - Isole Falkland (Malvinas) 1
IQ - Iraq 1
IR - Iran 1
LV - Lettonia 1
MT - Malta 1
NG - Nigeria 1
PE - Perù 1
TN - Tunisia 1
VE - Venezuela 1
Totale 41.652
Città #
Chandler 2.689
Dublin 2.384
Jacksonville 1.780
Scuola 1.668
Ann Arbor 1.211
Moscow 1.198
Wilmington 905
Boardman 870
New York 869
Ashburn 815
Izmir 789
Singapore 774
Saint Petersburg 729
Nanjing 631
Toronto 562
Woodbridge 511
Hong Kong 483
Princeton 330
Dearborn 320
Pisa 300
Istanbul 295
Houston 275
Nanchang 250
Beijing 236
Ogden 236
Helsinki 218
Santa Clara 198
Brooklyn 134
Milan 131
Dong Ket 130
Kunming 122
Sauris 104
Falls Church 97
Tianjin 95
Trieste 94
Brussels 91
Hebei 76
Seattle 76
Shenyang 76
Changsha 68
Dudelange 66
Hangzhou 60
Jiaxing 57
Verona 56
Lausanne 54
Vienna 53
Changchun 42
Washington 42
Berlin 41
Shanghai 41
Yubileyny 41
Orange 38
Frankfurt Am Main 37
Strasbourg 37
Guangzhou 35
Lanzhou 34
Dongguan 33
Hanover 32
Rome 32
Timisoara 31
Las Vegas 29
Ningbo 28
Redwood City 28
Zhengzhou 25
Jinan 24
Torino 24
Costa Mesa 21
Borås 19
Hefei 19
Taizhou 19
Auburn Hills 18
Norwalk 17
Redmond 17
Düsseldorf 16
Udine 16
Den Haag 15
Los Angeles 15
Frankfurt am Main 14
Grafing 14
Bologna 11
Munich 11
San Francisco 11
Shenzhen 11
Southend 11
Turin 11
Boston 10
Chengdu 10
Chicago 10
Chisinau 10
Mamer 10
Ottawa 10
Tokyo 10
Edmonton 9
Paris 9
Plauen 9
San Jose 9
Bremen 8
Candelo 8
Hanoi 8
London 8
Totale 24.264
Nome #
Brain aging: A Ianus-faced player between health and neurodegeneration 262
Characterization of prion protein function by focal neurite stimulation 215
The non-octarepeat copper binding site of the prion protein is a key regulator of prion conversion 212
alpha-Synuclein Amyloids Hijack Prion Protein to Gain Cell Entry, Facilitate Cell-to-Cell Spreading and Block Prion Replication 211
Detection of prion seeding activity in the olfactory mucosa of patients with Fatal Familial Insomnia 210
Prion protein and copper cooperatively protect neurons by modulating NMDA receptor through S-nitrosylation 203
Synthetic mammalian prions 203
Cellular prion protein: Role in excitotoxicity and in metal ions homeostasis 202
Nanoparticelle di oro rivestite con polielettroliti e loro uso come medicamento per il trattamento di malattie neurodegenerative causate da aggregati proteici 198
Whole blood gene expression profiling in preclinical and clinical cattle infected with atypical bovine spongiform encephalopathy 197
Differential overexpression of SERPINA3 in human prion diseases 196
Altered Brain Hemoglobin Gene Expression in the Frontal Cortex of Patients with Alzheimer’s and Acquired Creutzfeldt-Jakob’s Disease 195
Serpin inhibitors for the treatment of prion and prion-like diseases 195
Structural features of human prion protein variants revealed by NMR 193
Gene Expression Profiling of Prion-Infected Brains: a Novel Disease Signature for Neurodegeneration in Humans 190
Processo per la preparazione di proteine inibenti i ribosomi 188
Synthetic prions and other human neurodegenerative proteinopathies 187
Developmental prion protein expression in eutherian and methaterian mammalian central nervous system 186
Anti-prion activity generated by two soil compounds-Humic and fulvic acids 186
Synthetic prions with novel strain-specified properties 185
A new approach to follow a single extracellular vesicle-cell interaction using optical tweezers 185
Hemoglobin mRNA changes in the frontal cortex of patients with neurodegenerative diseases 182
The N Terminus of the Prion Protein Mediates Functional Interactions with the Neuronal Cell Adhesion Molecule (NCAM) Fibronectin Domain 182
A structural characterization of recombinant mouse prion protein amyloid fibers 179
Nucleotide sequences coding for ribosome inactivating proteins 178
Preface 178
Recent Advances of Biology and Medicinal Chemistry of Prion Protein and Prions: On the Road to Therapeutics 174
NMR structure of the human prion protein with the pathological Q212P mutation: insights into inherited human prion diseases 173
Gene expression profiling of brains from bovine spongiform encephalopathy (BSE)-infected cynomolgus macaques 172
Humic substances underlies the odds of environmental TSEs transmission 172
Prion protein interaction with soil humic substances: environmental implications 172
Cloning and characterization of a gene, inducible by cytokines 171
Whole transcriptome analysis in brains from BSE-infected macaques 171
Glia-to-neuron transfer of miRNAs via extracellular vesicles: a new mechanism underlying inflammation-induced synaptic alterations 171
The mechanisms of humic substances self-assembly with biological molecules: The case study of the prion protein 168
In Vitro Aggregation Assays for the Characterization of α-synuclein Prion-Like Properties 167
Discrimination of MSA-P and MSA-C by RT-QuIC analysis of olfactory mucosa: the first assessment of assay reproducibility between two specialized laboratories 167
Early structural features in mammalian prion conformation conversion 166
NMR Structures of the Human Prion Protein with Pathological Mutations: Insights Into Molecular Basis of Prion Disease 166
A search for auxiliary proteins in prion replication 165
Defined α-synuclein prion-like molecular assemblies spreading in cell culture 164
Brain delivery of AVV9 expressing anti-PrP molecules delays prion disease onsite in mice 164
Synthetic prions: De novo prion-infected neuronal cell lines and the generation of diverse infectious materials 163
Novel Approaches to Diagnosis and Therapy in Neurodegenerative Diseases 161
The role of the prion protein in the internalization of α-synuclein amyloids 161
Effects of the pathological Q212P mutation on human prion protein non-octarepeat copper-binding site 160
Soil humic substances hinder the propagation of prions 159
Identification of novel fluorescent probes preventing PrPSc replication in prion diseases 159
Oriented immobilization of prion protein demonstrated via precise interfacial nanostructure measurements 158
Structural Variations of Prion Proteins Caused by Mutations in Human Genome 158
Prions 157
Humic substances and therapeutic uses thereof 156
Method of amplifying infectious proteins 156
Prion protein and aging 155
Nanobody-stabilize the crystal structure of full-length human PrP 155
Pin1 and neurodegeneration: a new player for prion disorders? 154
Cloning and characterization of a gene, inducible by cytokines 154
NMR structure of the human prion protein Q212P mutant 153
New insights into structural determinants of prion protein folding and stability 153
Developmental role of the prion protein in the nervous system 152
A single point mutation, a way to prion disease? 152
The amino-terminal-fragment of human urokinase fused to the plant toxin saporin targets the recombinant fusion toxin to urokinase-receptor bearing-cells: is internalization mediated by the toxin? 152
Measuring prions causing bovine spongiform encephalopathy or chronic wasting disease by immunoassays and transgenic mice 152
Conformational properties of intrinsically disordered proteins bound to the surface of silica nanoparticles 152
Molecular pathogenesis of prion diseases 151
Nucleotide sequence coding for ribosome inactivating proteins 151
Induction of Protease-Resistant Prion Protein and alpha-synuclein Aggregation by Human alpha-synuclein Fibrils in Cultured Cells 151
In Absence of the Cellular Prion Protein, Alterations in Copper Metabolism and Copper-Dependent Oxidase Activity Affect Iron Distribution 150
Effects of tetrahydrocannabinol on melatonin secretion in man 150
Effect of extracellular vesicles derived from distinct brain cells on A beta toxicity and assembly: focus on microglia derived vesicles 150
AGFD 199 - Isolation and characterization of new anti-PrP monoclonal antibodies 150
Ligands binding to prion protein for use in the treatment of synucleinopathies 150
Efficient RT-QuIC seeding activity for α-synuclein in olfactory mucosa samples of patients with Parkinson's disease and multiple system atrophy 150
Anti-GM1 IgM antibodies in motor neuron disease (MND) and other neurological diseases 149
Structural determinants in prion protein folding and stability 148
Toward the molecular basis of inherited prion diseases: NMR structure of the human prion protein with V210I mutation 148
De novo generation of mammalian prions 148
Effects of the pathological Q212P mutation on human prion protein non-octarepeat copper binding site 148
Methionine oxidation in α-synuclein inhibits its propensity for ordered secondary structure 147
A Fluorescent Styrylquinoline with Combined Therapeutic and Diagnostic Activities against Alzheimer’s and Prion Diseases 146
Altered molecular signaling in neuronal cell models of prion infection 146
Humic substances and uses thereof in agro-environment 146
Pathogenesis of Prion Diseases 145
NMR structure of the human prion protein with the pathological Q212P mutation reveals unique structural features 145
Developmental influence of the cellular prion protein on the gene expression profile in mouse hippocampus 144
Cytosolic localization of prion protein in neuronal cells in brain of mice 144
Dominant-negative effects in prion diseases: insights from molecular dynamics simulations on mouse prion protein chimeras 144
Antemortem Prion Diagnostics 143
Antagonistic cellular functions for prion protein and its paralog doppel. 143
Design of ligands with a high affinity to the cellular form of the prion protein 143
Structural facets of disease-linked human prion protein mutants: A molecular dynamic study 141
NMR studies of human prion protein mutants in solution 139
Nucleotide sequences coding for ribosome inactivating proteins 139
TDP-43 real-time quaking induced conversion reaction optimization and detection of seeding activity in CSF of amyotrophic lateral sclerosis and frontotemporal dementia patients 139
Copper-catalyzed oxidation of the recombinant SHa (29-231) prion protein 138
Insights into molecular structures of human prion proteins with inherited mutations by NMR 138
Description and Characterization of a Highly Stable Enthalpic Intermediate State in Mouse Prion Protein Folding 137
NMR Structural Studies of Human Cellular Prion Proteins 137
Modulation of Prion by Small Molecules: From Monovalent to Bivalent and Multivalent Ligands 137
Gene expression profiling and therapeutic interventions in neurodegenerative diseases: a comprehensive study on potentiality and limits 136
Totale 16.444
Categoria #
all - tutte 165.931
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 165.931


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.685 0 0 0 0 364 228 813 375 357 168 344 36
2020/20213.585 441 94 33 332 66 677 471 24 395 382 149 521
2021/20223.292 483 370 18 334 568 94 202 365 144 107 195 412
2022/20238.209 1.218 896 735 782 431 1.663 883 528 769 62 114 128
2023/20244.799 279 71 178 82 708 1.960 184 261 739 66 59 212
2024/20259.811 2.325 800 1.519 3.663 1.504 0 0 0 0 0 0 0
Totale 42.966