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Legname, Giuseppe
 Distribuzione geografica
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Continente #
NA - Nord America 28.916
EU - Europa 28.551
AS - Asia 16.187
SA - Sud America 2.048
Continente sconosciuto - Info sul continente non disponibili 1.454
AF - Africa 277
OC - Oceania 39
Totale 77.472
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Nazione #
US - Stati Uniti d'America 27.842
RU - Federazione Russa 13.307
SG - Singapore 5.476
CN - Cina 5.048
IT - Italia 3.396
SE - Svezia 2.991
IE - Irlanda 2.402
BR - Brasile 1.728
UA - Ucraina 1.476
TR - Turchia 1.410
DE - Germania 1.172
VN - Vietnam 1.165
HK - Hong Kong 1.140
GB - Regno Unito 1.056
CA - Canada 814
KR - Corea 773
FR - Francia 693
FI - Finlandia 617
LU - Lussemburgo 263
BD - Bangladesh 240
IN - India 232
NL - Olanda 173
MX - Messico 161
AT - Austria 159
CH - Svizzera 144
PL - Polonia 144
JP - Giappone 134
ES - Italia 127
AR - Argentina 123
EU - Europa 108
BE - Belgio 100
ZA - Sudafrica 85
IQ - Iraq 82
GR - Grecia 68
LB - Libano 55
UZ - Uzbekistan 55
ID - Indonesia 54
PK - Pakistan 48
RO - Romania 48
VE - Venezuela 45
EC - Ecuador 42
CO - Colombia 38
MA - Marocco 34
SA - Arabia Saudita 34
CZ - Repubblica Ceca 33
LT - Lituania 31
PT - Portogallo 28
AZ - Azerbaigian 24
PH - Filippine 24
AU - Australia 23
CL - Cile 23
EG - Egitto 23
AE - Emirati Arabi Uniti 22
TN - Tunisia 22
DZ - Algeria 21
MY - Malesia 20
AL - Albania 19
IL - Israele 18
KE - Kenya 18
MD - Moldavia 17
JO - Giordania 16
CR - Costa Rica 15
NP - Nepal 15
PE - Perù 15
TH - Thailandia 15
DO - Repubblica Dominicana 14
NZ - Nuova Zelanda 14
JM - Giamaica 13
PY - Paraguay 12
UY - Uruguay 12
BG - Bulgaria 11
ET - Etiopia 10
HN - Honduras 10
HU - Ungheria 10
DK - Danimarca 9
PA - Panama 9
HR - Croazia 8
KZ - Kazakistan 8
OM - Oman 8
PS - Palestinian Territory 8
SY - Repubblica araba siriana 8
BO - Bolivia 7
BY - Bielorussia 7
CI - Costa d'Avorio 7
GT - Guatemala 7
SI - Slovenia 7
GA - Gabon 6
LK - Sri Lanka 6
LV - Lettonia 6
MN - Mongolia 6
RS - Serbia 6
SK - Slovacchia (Repubblica Slovacca) 6
SN - Senegal 6
TW - Taiwan 6
AO - Angola 5
CG - Congo 5
CY - Cipro 5
IR - Iran 5
NO - Norvegia 5
PR - Porto Rico 5
Totale 76.021
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Città #
Moscow 3.604
San Jose 2.697
Chandler 2.690
Singapore 2.529
Dublin 2.400
Ashburn 2.081
Santa Clara 1.882
Jacksonville 1.785
Scuola 1.668
Dallas 1.626
Council Bluffs 1.513
Ann Arbor 1.211
Hong Kong 1.112
New York 1.098
Beijing 928
Wilmington 908
Boardman 873
Izmir 792
Hefei 745
Saint Petersburg 729
Nanjing 632
Toronto 601
The Dalles 588
Istanbul 530
Woodbridge 513
Los Angeles 394
Seoul 391
Columbus 388
Ho Chi Minh City 348
Shanghai 346
Princeton 330
Houston 327
Dearborn 320
Lauterbourg 311
Pisa 303
Hanoi 263
Helsinki 252
Nanchang 251
Ogden 236
Buffalo 219
Brooklyn 203
Milan 191
São Paulo 174
Orem 171
Luxembourg 162
Munich 149
Dong Ket 130
Kunming 125
Trieste 123
Tokyo 113
Seattle 108
Sauris 104
Warsaw 100
Tianjin 99
Brussels 98
Falls Church 97
Dudelange 90
Montreal 89
Nuremberg 87
Chicago 86
Vienna 85
Turku 82
Atlanta 79
Shenyang 79
Phoenix 78
Chennai 77
Hebei 76
Denver 75
Rome 74
Changsha 72
Stockholm 69
Hangzhou 68
Boston 65
Poplar 63
London 62
San Francisco 62
Da Nang 60
Rio de Janeiro 59
Verona 59
Johannesburg 58
Jiaxing 57
Frankfurt am Main 55
Mexico City 55
Lausanne 54
Haiphong 50
Falkenstein 48
Washington 46
Ankara 45
Manchester 45
Mumbai 45
Changchun 43
Berlin 41
Las Vegas 41
Yubileyny 41
Amsterdam 40
Guangzhou 39
Belo Horizonte 38
Jakarta 38
Orange 38
Redondo Beach 38
Totale 45.212
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Nome #
Discrimination of MSA-P and MSA-C by RT-QuIC analysis of olfactory mucosa: the first assessment of assay reproducibility between two specialized laboratories 523
Detection of prion seeding activity in the olfactory mucosa of patients with Fatal Familial Insomnia 446
alpha-Synuclein Amyloids Hijack Prion Protein to Gain Cell Entry, Facilitate Cell-to-Cell Spreading and Block Prion Replication 391
Brain aging: A Ianus-faced player between health and neurodegeneration 387
Characterization of prion protein function by focal neurite stimulation 377
Whole blood gene expression profiling in preclinical and clinical cattle infected with atypical bovine spongiform encephalopathy 351
The non-octarepeat copper binding site of the prion protein is a key regulator of prion conversion 345
Differential overexpression of SERPINA3 in human prion diseases 344
Prion protein and copper cooperatively protect neurons by modulating NMDA receptor through S-nitrosylation 341
The N Terminus of the Prion Protein Mediates Functional Interactions with the Neuronal Cell Adhesion Molecule (NCAM) Fibronectin Domain 339
Hemoglobin mRNA changes in the frontal cortex of patients with neurodegenerative diseases 336
Synthetic mammalian prions 335
Altered Brain Hemoglobin Gene Expression in the Frontal Cortex of Patients with Alzheimer’s and Acquired Creutzfeldt-Jakob’s Disease 330
A new approach to follow a single extracellular vesicle-cell interaction using optical tweezers 324
Efficient RT-QuIC seeding activity for α-synuclein in olfactory mucosa samples of patients with Parkinson's disease and multiple system atrophy 322
Synthetic prions with novel strain-specified properties 317
Nanoparticelle di oro rivestite con polielettroliti e loro uso come medicamento per il trattamento di malattie neurodegenerative causate da aggregati proteici 315
Structural features of human prion protein variants revealed by NMR 313
Gene Expression Profiling of Prion-Infected Brains: a Novel Disease Signature for Neurodegeneration in Humans 308
Synthetic prions and other human neurodegenerative proteinopathies 307
Serpin inhibitors for the treatment of prion and prion-like diseases 307
A Fluorescent Styrylquinoline with Combined Therapeutic and Diagnostic Activities against Alzheimer’s and Prion Diseases 304
A structural characterization of recombinant mouse prion protein amyloid fibers 303
The mechanisms of humic substances self-assembly with biological molecules: The case study of the prion protein 300
Cellular prion protein: Role in excitotoxicity and in metal ions homeostasis 298
Anti-prion activity generated by two soil compounds-Humic and fulvic acids 297
Soil humic substances hinder the propagation of prions 295
A single point mutation, a way to prion disease? 294
Synthetic prions: De novo prion-infected neuronal cell lines and the generation of diverse infectious materials 294
Gene expression profiling of brains from bovine spongiform encephalopathy (BSE)-infected cynomolgus macaques 289
Recent Advances of Biology and Medicinal Chemistry of Prion Protein and Prions: On the Road to Therapeutics 288
Developmental prion protein expression in eutherian and methaterian mammalian central nervous system 285
A search for auxiliary proteins in prion replication 284
NMR structure of the human prion protein with the pathological Q212P mutation: insights into inherited human prion diseases 284
Conformational properties of intrinsically disordered proteins bound to the surface of silica nanoparticles 283
Preface 283
NMR structure of the human prion protein Q212P mutant 282
Effects of tetrahydrocannabinol on melatonin secretion in man 281
Processo per la preparazione di proteine inibenti i ribosomi 281
Anti-GM1 IgM antibodies in motor neuron disease (MND) and other neurological diseases 281
Nucleotide sequences coding for ribosome inactivating proteins 280
A novel expression system for production of soluble prion proteins in E.coli 279
Prion protein interaction with soil humic substances: environmental implications 277
Anti-CD30 immunotoxins with native and recombinant dianthin 30 277
Humic substances underlies the odds of environmental TSEs transmission 275
Identification of novel fluorescent probes preventing PrPSc replication in prion diseases 275
Tau-Centric Multitarget Approach for Alzheimer's Disease: Development of First-in-Class Dual Glycogen Synthase Kinase 3β and Tau-Aggregation Inhibitors 275
Effects of the pathological Q212P mutation on human prion protein non-octarepeat copper-binding site 274
Developmental influence of the cellular prion protein on the gene expression profile in mouse hippocampus 273
New insights into structural determinants of prion protein folding and stability 273
Defined α-synuclein prion-like molecular assemblies spreading in cell culture 272
Whole transcriptome analysis in brains from BSE-infected macaques 272
Nanobody-stabilize the crystal structure of full-length human PrP 272
Methionine oxidation in α-synuclein inhibits its propensity for ordered secondary structure 272
A system-level approach for deciphering the transcriptional response to prion infection 271
Early structural features in mammalian prion conformation conversion 270
In Absence of the Cellular Prion Protein, Alterations in Copper Metabolism and Copper-Dependent Oxidase Activity Affect Iron Distribution 270
NMR Structures of the Human Prion Protein with Pathological Mutations: Insights Into Molecular Basis of Prion Disease 270
The role of the prion protein in the internalization of α-synuclein amyloids 269
In Vitro Aggregation Assays for the Characterization of α-synuclein Prion-Like Properties 268
Oriented immobilization of prion protein demonstrated via precise interfacial nanostructure measurements 268
AGFD 199 - Isolation and characterization of new anti-PrP monoclonal antibodies 268
NMR Structural Studies of Human Cellular Prion Proteins 267
Cloning and characterization of a gene, inducible by cytokines 266
TDP-43 real-time quaking induced conversion reaction optimization and detection of seeding activity in CSF of amyotrophic lateral sclerosis and frontotemporal dementia patients 265
Antagonistic cellular functions for prion protein and its paralog doppel. 264
A change in the conformation of prions accompanies the emergence of a new prion strain 264
In silico/in vitro screening and hit evaluation identified new phenothiazine anti-prion derivatives 264
Aberrant ERK 1/2 complex activation and localization in scrapie-infected GT1-1 cells 263
Structural Variations of Prion Proteins Caused by Mutations in Human Genome 263
Antemortem Prion Diagnostics 263
Glia-to-neuron transfer of miRNAs via extracellular vesicles: a new mechanism underlying inflammation-induced synaptic alterations 263
Use of different RT-QuIC substrates for detecting CWD prions in the brain of Norwegian cervids 263
Astrocytes-derived extracellular vesicles in motion at the neuron surface: Involvement of the prion protein 262
Ligands binding to prion protein for use in the treatment of synucleinopathies 261
Pin1 and neurodegeneration: a new player for prion disorders? 260
Characterization of four new monoclonal antibodies against the distal N-terminal region of PrP(c) 260
NMR structure of the human prion protein with the pathological Q212P mutation reveals unique structural features 258
Prions 257
Dominant-negative effects in prion diseases: insights from molecular dynamics simulations on mouse prion protein chimeras 255
Altered molecular signaling in neuronal cell models of prion infection 254
De novo generation of mammalian prions 253
Opposite Structural Effects of Epigallocatechin-3-gallate and Dopamine Binding to α-Synuclein 252
Prion and prion-like protein strains: Deciphering the molecular basis of heterogeneity in neurodegeneration 252
Aged PrP null mice show defective processing of neuregulins in the peripheral nervous system 251
Humic substances and therapeutic uses thereof 250
Humic substances and uses thereof in agro-environment 249
Structural facets of disease-linked human prion protein mutants: A molecular dynamic study 249
The cellular prion protein increases the uptake and toxicity of tdp-43 fibrils 249
Structural determinants in prion protein folding and stability 248
Assessment of doxycycline treatment on prion deposition in the olfactory epithelium of patients with Fatal Familial Insomnia: Possible mirroring of the CNS alterations 247
Toward the molecular basis of inherited prion diseases: NMR structure of the human prion protein with V210I mutation 246
Prion protein and aging 246
Developmental role of the prion protein in the nervous system 246
Brain delivery of AVV9 expressing anti-PrP molecules delays prion disease onsite in mice 246
Inferring prion partners from Gene-Networks 246
NMDA Receptor and L-Type Calcium Channel Modulate Prion Formation 246
A novel class of potential prion drugs: preliminary in vitro and in vivo data for multilayer coated gold nanoparticles 245
Insights into molecular structures of human prion proteins with inherited mutations by NMR 245
Effect of extracellular vesicles derived from distinct brain cells on A beta toxicity and assembly: focus on microglia derived vesicles 243
Totale 28.545
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Categoria #
all - tutte 279.549
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 279.549
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20222.809 0 370 18 334 568 94 202 365 144 107 195 412
2022/20238.209 1.218 896 735 782 431 1.663 883 528 769 62 114 128
2023/20244.799 279 71 178 82 708 1.960 184 261 739 66 59 212
2024/202516.623 2.325 800 1.519 3.663 1.677 719 799 843 660 544 1.502 1.572
2025/202625.399 986 1.971 1.668 2.404 3.453 5.121 3.966 951 1.107 1.146 643 1.983
2026/20272.295 967 1.328 0 0 0 0 0 0 0 0 0 0
Totale 77.472