Legname, Giuseppe
 Distribuzione geografica
Continente #
EU - Europa 27.145
NA - Nord America 21.011
AS - Asia 13.354
SA - Sud America 1.770
AF - Africa 183
Continente sconosciuto - Info sul continente non disponibili 113
OC - Oceania 32
Totale 63.608
Nazione #
US - Stati Uniti d'America 20.134
RU - Federazione Russa 13.049
CN - Cina 4.690
SG - Singapore 4.590
IT - Italia 3.130
SE - Svezia 2.805
IE - Irlanda 2.394
BR - Brasile 1.549
UA - Ucraina 1.455
TR - Turchia 1.395
DE - Germania 1.131
HK - Hong Kong 1.024
GB - Regno Unito 990
CA - Canada 739
KR - Corea 617
FI - Finlandia 604
FR - Francia 323
VN - Vietnam 316
LU - Lussemburgo 263
AT - Austria 156
NL - Olanda 138
CH - Svizzera 133
IN - India 132
PL - Polonia 132
JP - Giappone 115
EU - Europa 108
AR - Argentina 100
MX - Messico 99
BE - Belgio 98
BD - Bangladesh 89
ES - Italia 77
ZA - Sudafrica 65
GR - Grecia 61
LB - Libano 53
UZ - Uzbekistan 49
IQ - Iraq 44
RO - Romania 44
ID - Indonesia 42
CZ - Repubblica Ceca 30
PK - Pakistan 29
VE - Venezuela 29
EC - Ecuador 28
LT - Lituania 25
PT - Portogallo 23
CO - Colombia 20
MA - Marocco 20
SA - Arabia Saudita 20
AE - Emirati Arabi Uniti 19
AZ - Azerbaigian 18
AU - Australia 16
EG - Egitto 15
IL - Israele 14
NZ - Nuova Zelanda 14
PE - Perù 13
AL - Albania 12
CL - Cile 12
KE - Kenya 12
NP - Nepal 12
TN - Tunisia 12
DZ - Algeria 11
MD - Moldavia 11
TH - Thailandia 11
PH - Filippine 9
CR - Costa Rica 8
DK - Danimarca 8
PY - Paraguay 8
DO - Repubblica Dominicana 7
HU - Ungheria 7
PS - Palestinian Territory 7
UY - Uruguay 7
BY - Bielorussia 6
ET - Etiopia 6
JM - Giamaica 6
JO - Giordania 6
BG - Bulgaria 5
HR - Croazia 5
KZ - Kazakistan 5
LK - Sri Lanka 5
PA - Panama 5
RS - Serbia 5
SK - Slovacchia (Repubblica Slovacca) 5
SY - Repubblica araba siriana 5
AO - Angola 4
IR - Iran 4
KG - Kirghizistan 4
MN - Mongolia 4
MY - Malesia 4
SC - Seychelles 4
SI - Slovenia 4
TW - Taiwan 4
AM - Armenia 3
BF - Burkina Faso 3
CG - Congo 3
CI - Costa d'Avorio 3
GA - Gabon 3
LV - Lettonia 3
NO - Norvegia 3
OM - Oman 3
TZ - Tanzania 3
UG - Uganda 3
Totale 63.546
Città #
Moscow 3.536
Chandler 2.689
Dublin 2.391
Singapore 2.117
Jacksonville 1.780
Scuola 1.668
Dallas 1.583
Ashburn 1.402
Ann Arbor 1.211
New York 1.037
Hong Kong 1.011
Wilmington 906
Boardman 871
Beijing 820
Izmir 792
Hefei 745
Saint Petersburg 729
Nanjing 632
Toronto 586
Istanbul 526
Woodbridge 512
The Dalles 396
Seoul 390
Columbus 384
Los Angeles 350
Princeton 330
Shanghai 329
Dearborn 320
Houston 306
Pisa 302
Santa Clara 286
Nanchang 251
Helsinki 248
Ogden 236
Council Bluffs 209
Buffalo 197
Brooklyn 192
Luxembourg 162
Milan 157
São Paulo 155
Munich 149
Dong Ket 130
Kunming 125
Trieste 119
Sauris 104
Tokyo 101
Seattle 98
Falls Church 97
Brussels 96
Tianjin 96
Warsaw 94
Dudelange 90
Nuremberg 84
Vienna 83
Turku 82
Shenyang 79
Hebei 76
Changsha 72
Montreal 70
Denver 67
Stockholm 67
Hangzhou 66
Atlanta 64
Ho Chi Minh City 63
Chicago 62
Poplar 61
Boston 60
San Jose 59
Verona 58
Jiaxing 57
Orem 56
Lausanne 54
Phoenix 52
Rio de Janeiro 50
Rome 50
Johannesburg 49
Falkenstein 48
Hanoi 48
San Francisco 48
London 47
Ankara 45
Changchun 43
Chennai 43
Washington 43
Berlin 41
Yubileyny 41
Guangzhou 39
Orange 38
Redondo Beach 38
Frankfurt Am Main 37
Las Vegas 37
Strasbourg 37
Mexico City 35
Belo Horizonte 34
Jakarta 34
Lanzhou 34
Dongguan 33
Hanover 32
Manchester 31
Timisoara 31
Totale 36.521
Nome #
Discrimination of MSA-P and MSA-C by RT-QuIC analysis of olfactory mucosa: the first assessment of assay reproducibility between two specialized laboratories 447
alpha-Synuclein Amyloids Hijack Prion Protein to Gain Cell Entry, Facilitate Cell-to-Cell Spreading and Block Prion Replication 343
Brain aging: A Ianus-faced player between health and neurodegeneration 341
Characterization of prion protein function by focal neurite stimulation 333
Detection of prion seeding activity in the olfactory mucosa of patients with Fatal Familial Insomnia 324
The non-octarepeat copper binding site of the prion protein is a key regulator of prion conversion 306
Differential overexpression of SERPINA3 in human prion diseases 304
Altered Brain Hemoglobin Gene Expression in the Frontal Cortex of Patients with Alzheimer’s and Acquired Creutzfeldt-Jakob’s Disease 303
Synthetic mammalian prions 300
Prion protein and copper cooperatively protect neurons by modulating NMDA receptor through S-nitrosylation 289
A new approach to follow a single extracellular vesicle-cell interaction using optical tweezers 286
The N Terminus of the Prion Protein Mediates Functional Interactions with the Neuronal Cell Adhesion Molecule (NCAM) Fibronectin Domain 282
Hemoglobin mRNA changes in the frontal cortex of patients with neurodegenerative diseases 281
Whole blood gene expression profiling in preclinical and clinical cattle infected with atypical bovine spongiform encephalopathy 281
Structural features of human prion protein variants revealed by NMR 279
Gene Expression Profiling of Prion-Infected Brains: a Novel Disease Signature for Neurodegeneration in Humans 277
Synthetic prions and other human neurodegenerative proteinopathies 276
Synthetic prions with novel strain-specified properties 275
Serpin inhibitors for the treatment of prion and prion-like diseases 272
Cellular prion protein: Role in excitotoxicity and in metal ions homeostasis 266
A structural characterization of recombinant mouse prion protein amyloid fibers 264
Efficient RT-QuIC seeding activity for α-synuclein in olfactory mucosa samples of patients with Parkinson's disease and multiple system atrophy 264
A Fluorescent Styrylquinoline with Combined Therapeutic and Diagnostic Activities against Alzheimer’s and Prion Diseases 263
Nanoparticelle di oro rivestite con polielettroliti e loro uso come medicamento per il trattamento di malattie neurodegenerative causate da aggregati proteici 262
Anti-prion activity generated by two soil compounds-Humic and fulvic acids 259
A search for auxiliary proteins in prion replication 258
Processo per la preparazione di proteine inibenti i ribosomi 254
The mechanisms of humic substances self-assembly with biological molecules: The case study of the prion protein 254
Developmental prion protein expression in eutherian and methaterian mammalian central nervous system 254
Recent Advances of Biology and Medicinal Chemistry of Prion Protein and Prions: On the Road to Therapeutics 253
A single point mutation, a way to prion disease? 253
Soil humic substances hinder the propagation of prions 252
Nucleotide sequences coding for ribosome inactivating proteins 252
Preface 249
NMR structure of the human prion protein with the pathological Q212P mutation: insights into inherited human prion diseases 247
Anti-GM1 IgM antibodies in motor neuron disease (MND) and other neurological diseases 244
Whole transcriptome analysis in brains from BSE-infected macaques 244
Identification of novel fluorescent probes preventing PrPSc replication in prion diseases 243
Conformational properties of intrinsically disordered proteins bound to the surface of silica nanoparticles 243
Gene expression profiling of brains from bovine spongiform encephalopathy (BSE)-infected cynomolgus macaques 242
NMR Structures of the Human Prion Protein with Pathological Mutations: Insights Into Molecular Basis of Prion Disease 242
Anti-CD30 immunotoxins with native and recombinant dianthin 30 242
A novel expression system for production of soluble prion proteins in E.coli 241
Prion protein interaction with soil humic substances: environmental implications 241
Effects of the pathological Q212P mutation on human prion protein non-octarepeat copper-binding site 239
Nanobody-stabilize the crystal structure of full-length human PrP 238
New insights into structural determinants of prion protein folding and stability 238
NMR structure of the human prion protein Q212P mutant 237
The role of the prion protein in the internalization of α-synuclein amyloids 236
Glia-to-neuron transfer of miRNAs via extracellular vesicles: a new mechanism underlying inflammation-induced synaptic alterations 236
In Vitro Aggregation Assays for the Characterization of α-synuclein Prion-Like Properties 235
AGFD 199 - Isolation and characterization of new anti-PrP monoclonal antibodies 235
Defined α-synuclein prion-like molecular assemblies spreading in cell culture 234
Humic substances underlies the odds of environmental TSEs transmission 234
Early structural features in mammalian prion conformation conversion 233
Structural Variations of Prion Proteins Caused by Mutations in Human Genome 232
Altered molecular signaling in neuronal cell models of prion infection 232
A change in the conformation of prions accompanies the emergence of a new prion strain 232
Synthetic prions: De novo prion-infected neuronal cell lines and the generation of diverse infectious materials 232
In Absence of the Cellular Prion Protein, Alterations in Copper Metabolism and Copper-Dependent Oxidase Activity Affect Iron Distribution 231
Antemortem Prion Diagnostics 231
Characterization of four new monoclonal antibodies against the distal N-terminal region of PrP(c) 231
Dominant-negative effects in prion diseases: insights from molecular dynamics simulations on mouse prion protein chimeras 231
Antagonistic cellular functions for prion protein and its paralog doppel. 229
A system-level approach for deciphering the transcriptional response to prion infection 229
Pin1 and neurodegeneration: a new player for prion disorders? 229
Methionine oxidation in α-synuclein inhibits its propensity for ordered secondary structure 229
Oriented immobilization of prion protein demonstrated via precise interfacial nanostructure measurements 227
Cloning and characterization of a gene, inducible by cytokines 227
NMR structure of the human prion protein with the pathological Q212P mutation reveals unique structural features 227
Aberrant ERK 1/2 complex activation and localization in scrapie-infected GT1-1 cells 222
Opposite Structural Effects of Epigallocatechin-3-gallate and Dopamine Binding to α-Synuclein 221
Prions 221
Use of different RT-QuIC substrates for detecting CWD prions in the brain of Norwegian cervids 220
Effect of extracellular vesicles derived from distinct brain cells on A beta toxicity and assembly: focus on microglia derived vesicles 219
TDP-43 real-time quaking induced conversion reaction optimization and detection of seeding activity in CSF of amyotrophic lateral sclerosis and frontotemporal dementia patients 219
Brain delivery of AVV9 expressing anti-PrP molecules delays prion disease onsite in mice 218
Structural facets of disease-linked human prion protein mutants: A molecular dynamic study 218
A novel class of potential prion drugs: preliminary in vitro and in vivo data for multilayer coated gold nanoparticles 216
De novo generation of mammalian prions 216
Humic substances and therapeutic uses thereof 215
Insights into molecular structures of human prion proteins with inherited mutations by NMR 215
Ligands binding to prion protein for use in the treatment of synucleinopathies 215
Toward the molecular basis of inherited prion diseases: NMR structure of the human prion protein with V210I mutation 214
Prion protein and aging 214
Induction of Protease-Resistant Prion Protein and alpha-synuclein Aggregation by Human alpha-synuclein Fibrils in Cultured Cells 214
Structural determinants in prion protein folding and stability 213
Humic substances and uses thereof in agro-environment 213
Developmental role of the prion protein in the nervous system 212
Aged PrP null mice show defective processing of neuregulins in the peripheral nervous system 212
Measuring prions causing bovine spongiform encephalopathy or chronic wasting disease by immunoassays and transgenic mice 212
Astrocytes-derived extracellular vesicles in motion at the neuron surface: Involvement of the prion protein 212
NMR Structural Studies of Human Cellular Prion Proteins 211
In silico/in vitro screening and hit evaluation identified new phenothiazine anti-prion derivatives 210
Developmental influence of the cellular prion protein on the gene expression profile in mouse hippocampus 209
Method of amplifying infectious proteins 209
NMR studies of human prion protein mutants in solution 207
Nucleotide sequences coding for ribosome inactivating proteins 206
Inferring prion partners from Gene-Networks 206
Prion and prion-like protein strains: Deciphering the molecular basis of heterogeneity in neurodegeneration 206
Totale 24.544
Categoria #
all - tutte 245.844
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 245.844


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20212.619 0 0 0 0 0 677 471 24 395 382 149 521
2021/20223.292 483 370 18 334 568 94 202 365 144 107 195 412
2022/20238.209 1.218 896 735 782 431 1.663 883 528 769 62 114 128
2023/20244.799 279 71 178 82 708 1.960 184 261 739 66 59 212
2024/202516.623 2.325 800 1.519 3.663 1.677 719 799 843 660 544 1.502 1.572
2025/202615.171 986 1.971 1.668 2.404 3.453 4.689 0 0 0 0 0 0
Totale 64.949