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Legname, Giuseppe
 Distribuzione geografica
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Continente #
NA - Nord America 32.076
EU - Europa 29.141
AS - Asia 16.260
SA - Sud America 2.132
Continente sconosciuto - Info sul continente non disponibili 1.455
AF - Africa 280
OC - Oceania 39
Totale 81.383
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Nazione #
US - Stati Uniti d'America 30.762
RU - Federazione Russa 13.312
SG - Singapore 5.482
CN - Cina 5.050
IT - Italia 3.880
SE - Svezia 2.993
IE - Irlanda 2.405
BR - Brasile 1.764
UA - Ucraina 1.478
TR - Turchia 1.412
DE - Germania 1.184
VN - Vietnam 1.172
HK - Hong Kong 1.142
GB - Regno Unito 1.099
CA - Canada 928
KR - Corea 773
FR - Francia 699
FI - Finlandia 617
LU - Lussemburgo 263
BD - Bangladesh 242
IN - India 235
NL - Olanda 178
MX - Messico 171
AT - Austria 159
CH - Svizzera 144
PL - Polonia 144
JP - Giappone 136
ES - Italia 131
AR - Argentina 127
EU - Europa 108
BE - Belgio 101
ZA - Sudafrica 85
IQ - Iraq 82
GR - Grecia 68
ID - Indonesia 62
CO - Colombia 59
EC - Ecuador 58
LB - Libano 57
UZ - Uzbekistan 55
RO - Romania 54
VE - Venezuela 51
PK - Pakistan 49
SA - Arabia Saudita 39
LT - Lituania 38
CR - Costa Rica 35
MA - Marocco 35
PH - Filippine 35
CZ - Repubblica Ceca 33
JM - Giamaica 31
MY - Malesia 31
PT - Portogallo 29
AZ - Azerbaigian 25
CL - Cile 24
AE - Emirati Arabi Uniti 23
AU - Australia 23
EG - Egitto 23
IL - Israele 22
TN - Tunisia 22
DZ - Algeria 21
GT - Guatemala 21
HN - Honduras 20
AL - Albania 19
KE - Kenya 19
MD - Moldavia 17
JO - Giordania 16
NP - Nepal 15
PE - Perù 15
TH - Thailandia 15
TT - Trinidad e Tobago 15
DO - Repubblica Dominicana 14
NZ - Nuova Zelanda 14
PR - Porto Rico 14
SV - El Salvador 13
NI - Nicaragua 12
PY - Paraguay 12
UY - Uruguay 12
BG - Bulgaria 11
HU - Ungheria 11
PA - Panama 11
DK - Danimarca 10
ET - Etiopia 10
OM - Oman 9
EE - Estonia 8
HR - Croazia 8
KZ - Kazakistan 8
PS - Palestinian Territory 8
SY - Repubblica araba siriana 8
BO - Bolivia 7
BY - Bielorussia 7
CI - Costa d'Avorio 7
RS - Serbia 7
SI - Slovenia 7
BS - Bahamas 6
GA - Gabon 6
LK - Sri Lanka 6
LV - Lettonia 6
MN - Mongolia 6
SK - Slovacchia (Repubblica Slovacca) 6
SN - Senegal 6
TW - Taiwan 6
Totale 79.908
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Città #
Moscow 3.604
San Jose 3.084
Chandler 2.692
Singapore 2.531
Ashburn 2.509
Dublin 2.400
Council Bluffs 2.000
Santa Clara 1.908
Jacksonville 1.790
Scuola 1.668
Dallas 1.640
Ann Arbor 1.211
Hong Kong 1.114
New York 1.112
Beijing 929
Wilmington 911
Boardman 876
Izmir 792
Hefei 745
Saint Petersburg 729
Nanjing 632
Toronto 609
The Dalles 590
Istanbul 530
Woodbridge 514
Los Angeles 421
Columbus 396
Seoul 391
Milan 369
Ho Chi Minh City 351
Shanghai 346
Houston 333
Princeton 330
Dearborn 320
Lauterbourg 311
Pisa 304
Hanoi 265
Helsinki 252
Nanchang 251
Ogden 236
Buffalo 225
Brooklyn 208
Phoenix 199
São Paulo 178
Orem 174
Luxembourg 162
Munich 149
Trieste 137
Dong Ket 130
Kunming 125
Tokyo 114
Seattle 113
Rome 109
Sauris 104
Montreal 101
Chicago 100
Warsaw 100
Brussels 99
Tianjin 99
Falls Church 97
Atlanta 95
Dudelange 90
Nuremberg 87
Vienna 85
Turku 82
Shenyang 79
Chennai 77
Denver 77
Hebei 76
Washington 75
Changsha 72
San Francisco 69
Stockholm 69
Hangzhou 68
Miano 66
Boston 65
London 63
Poplar 63
Rio de Janeiro 61
Verona 61
Da Nang 60
Johannesburg 58
Pequot Lakes 58
Jiaxing 57
Frankfurt am Main 55
Mexico City 55
Lausanne 54
Haiphong 50
Falkenstein 48
Manchester 47
Mumbai 46
Ankara 45
Changchun 43
Las Vegas 43
Berlin 41
Yubileyny 41
Amsterdam 40
Guangzhou 39
Jakarta 39
Belo Horizonte 38
Totale 47.156
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Nome #
Discrimination of MSA-P and MSA-C by RT-QuIC analysis of olfactory mucosa: the first assessment of assay reproducibility between two specialized laboratories 533
Detection of prion seeding activity in the olfactory mucosa of patients with Fatal Familial Insomnia 456
alpha-Synuclein Amyloids Hijack Prion Protein to Gain Cell Entry, Facilitate Cell-to-Cell Spreading and Block Prion Replication 400
Brain aging: A Ianus-faced player between health and neurodegeneration 400
Characterization of prion protein function by focal neurite stimulation 388
Whole blood gene expression profiling in preclinical and clinical cattle infected with atypical bovine spongiform encephalopathy 363
The non-octarepeat copper binding site of the prion protein is a key regulator of prion conversion 358
Differential overexpression of SERPINA3 in human prion diseases 356
Synthetic mammalian prions 355
The N Terminus of the Prion Protein Mediates Functional Interactions with the Neuronal Cell Adhesion Molecule (NCAM) Fibronectin Domain 355
Prion protein and copper cooperatively protect neurons by modulating NMDA receptor through S-nitrosylation 348
Structural features of human prion protein variants revealed by NMR 348
Hemoglobin mRNA changes in the frontal cortex of patients with neurodegenerative diseases 346
Effects of tetrahydrocannabinol on melatonin secretion in man 344
Altered Brain Hemoglobin Gene Expression in the Frontal Cortex of Patients with Alzheimer’s and Acquired Creutzfeldt-Jakob’s Disease 341
Efficient RT-QuIC seeding activity for α-synuclein in olfactory mucosa samples of patients with Parkinson's disease and multiple system atrophy 340
A new approach to follow a single extracellular vesicle-cell interaction using optical tweezers 336
Nanoparticelle di oro rivestite con polielettroliti e loro uso come medicamento per il trattamento di malattie neurodegenerative causate da aggregati proteici 332
Recent Advances of Biology and Medicinal Chemistry of Prion Protein and Prions: On the Road to Therapeutics 328
Synthetic prions with novel strain-specified properties 325
Gene Expression Profiling of Prion-Infected Brains: a Novel Disease Signature for Neurodegeneration in Humans 319
Serpin inhibitors for the treatment of prion and prion-like diseases 319
The mechanisms of humic substances self-assembly with biological molecules: The case study of the prion protein 318
Synthetic prions and other human neurodegenerative proteinopathies 318
A structural characterization of recombinant mouse prion protein amyloid fibers 316
A Fluorescent Styrylquinoline with Combined Therapeutic and Diagnostic Activities against Alzheimer’s and Prion Diseases 314
A single point mutation, a way to prion disease? 310
Cellular prion protein: Role in excitotoxicity and in metal ions homeostasis 310
Anti-prion activity generated by two soil compounds-Humic and fulvic acids 306
Soil humic substances hinder the propagation of prions 305
Synthetic prions: De novo prion-infected neuronal cell lines and the generation of diverse infectious materials 303
Conformational properties of intrinsically disordered proteins bound to the surface of silica nanoparticles 296
Gene expression profiling of brains from bovine spongiform encephalopathy (BSE)-infected cynomolgus macaques 294
A search for auxiliary proteins in prion replication 294
NMR structure of the human prion protein with the pathological Q212P mutation: insights into inherited human prion diseases 294
Preface 294
Developmental prion protein expression in eutherian and methaterian mammalian central nervous system 293
NMR structure of the human prion protein Q212P mutant 291
Anti-GM1 IgM antibodies in motor neuron disease (MND) and other neurological diseases 290
Anti-CD30 immunotoxins with native and recombinant dianthin 30 290
A novel expression system for production of soluble prion proteins in E.coli 289
Humic substances underlies the odds of environmental TSEs transmission 289
Whole transcriptome analysis in brains from BSE-infected macaques 289
Prion protein interaction with soil humic substances: environmental implications 289
Tau-Centric Multitarget Approach for Alzheimer's Disease: Development of First-in-Class Dual Glycogen Synthase Kinase 3β and Tau-Aggregation Inhibitors 288
Processo per la preparazione di proteine inibenti i ribosomi 287
Nucleotide sequences coding for ribosome inactivating proteins 287
Developmental influence of the cellular prion protein on the gene expression profile in mouse hippocampus 286
Effects of the pathological Q212P mutation on human prion protein non-octarepeat copper-binding site 286
Defined α-synuclein prion-like molecular assemblies spreading in cell culture 284
Early structural features in mammalian prion conformation conversion 283
Methionine oxidation in α-synuclein inhibits its propensity for ordered secondary structure 283
A system-level approach for deciphering the transcriptional response to prion infection 282
Identification of novel fluorescent probes preventing PrPSc replication in prion diseases 282
Nanobody-stabilize the crystal structure of full-length human PrP 281
The role of the prion protein in the internalization of α-synuclein amyloids 280
New insights into structural determinants of prion protein folding and stability 280
In Absence of the Cellular Prion Protein, Alterations in Copper Metabolism and Copper-Dependent Oxidase Activity Affect Iron Distribution 279
NMR Structures of the Human Prion Protein with Pathological Mutations: Insights Into Molecular Basis of Prion Disease 279
NMR Structural Studies of Human Cellular Prion Proteins 279
Oriented immobilization of prion protein demonstrated via precise interfacial nanostructure measurements 278
Astrocytes-derived extracellular vesicles in motion at the neuron surface: Involvement of the prion protein 276
Aberrant ERK 1/2 complex activation and localization in scrapie-infected GT1-1 cells 275
Structural Variations of Prion Proteins Caused by Mutations in Human Genome 275
Cloning and characterization of a gene, inducible by cytokines 275
AGFD 199 - Isolation and characterization of new anti-PrP monoclonal antibodies 275
Glia-to-neuron transfer of miRNAs via extracellular vesicles: a new mechanism underlying inflammation-induced synaptic alterations 274
Antagonistic cellular functions for prion protein and its paralog doppel. 273
TDP-43 real-time quaking induced conversion reaction optimization and detection of seeding activity in CSF of amyotrophic lateral sclerosis and frontotemporal dementia patients 273
In silico/in vitro screening and hit evaluation identified new phenothiazine anti-prion derivatives 273
In Vitro Aggregation Assays for the Characterization of α-synuclein Prion-Like Properties 272
NMR structure of the human prion protein with the pathological Q212P mutation reveals unique structural features 272
A change in the conformation of prions accompanies the emergence of a new prion strain 272
Antemortem Prion Diagnostics 271
Ligands binding to prion protein for use in the treatment of synucleinopathies 271
Use of different RT-QuIC substrates for detecting CWD prions in the brain of Norwegian cervids 271
Pin1 and neurodegeneration: a new player for prion disorders? 270
Dominant-negative effects in prion diseases: insights from molecular dynamics simulations on mouse prion protein chimeras 267
The cellular prion protein increases the uptake and toxicity of tdp-43 fibrils 267
Prions 266
Characterization of four new monoclonal antibodies against the distal N-terminal region of PrP(c) 266
Prion and prion-like protein strains: Deciphering the molecular basis of heterogeneity in neurodegeneration 264
Opposite Structural Effects of Epigallocatechin-3-gallate and Dopamine Binding to α-Synuclein 263
Assessment of doxycycline treatment on prion deposition in the olfactory epithelium of patients with Fatal Familial Insomnia: Possible mirroring of the CNS alterations 263
Structural facets of disease-linked human prion protein mutants: A molecular dynamic study 263
Altered molecular signaling in neuronal cell models of prion infection 262
Aged PrP null mice show defective processing of neuregulins in the peripheral nervous system 262
Humic substances and uses thereof in agro-environment 261
Brain delivery of AVV9 expressing anti-PrP molecules delays prion disease onsite in mice 260
Toward the molecular basis of inherited prion diseases: NMR structure of the human prion protein with V210I mutation 259
De novo generation of mammalian prions 259
Structural determinants in prion protein folding and stability 258
Humic substances and therapeutic uses thereof 257
Insights into molecular structures of human prion proteins with inherited mutations by NMR 257
Inferring prion partners from Gene-Networks 257
A novel class of potential prion drugs: preliminary in vitro and in vivo data for multilayer coated gold nanoparticles 256
Developmental role of the prion protein in the nervous system 256
NMDA Receptor and L-Type Calcium Channel Modulate Prion Formation 256
Prion protein and aging 254
Nucleotide sequences coding for ribosome inactivating proteins 254
Totale 29.741
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Categoria #
all - tutte 290.845
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 290.845
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20222.421 0 0 0 334 568 94 202 365 144 107 195 412
2022/20238.209 1.218 896 735 782 431 1.663 883 528 769 62 114 128
2023/20244.799 279 71 178 82 708 1.960 184 261 739 66 59 212
2024/202516.623 2.325 800 1.519 3.663 1.677 719 799 843 660 544 1.502 1.572
2025/202625.399 986 1.971 1.668 2.404 3.453 5.121 3.966 951 1.107 1.146 643 1.983
2026/20276.206 967 1.641 1.794 1.804 0 0 0 0 0 0 0 0
Totale 81.383