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Legname, Giuseppe
 Distribuzione geografica
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Continente #
EU - Europa 28.352
NA - Nord America 25.577
AS - Asia 15.886
SA - Sud America 2.011
AF - Africa 275
Continente sconosciuto - Info sul continente non disponibili 113
OC - Oceania 39
Totale 72.253
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Nazione #
US - Stati Uniti d'America 24.560
RU - Federazione Russa 13.306
SG - Singapore 5.392
CN - Cina 4.921
IT - Italia 3.322
SE - Svezia 2.901
IE - Irlanda 2.401
BR - Brasile 1.711
UA - Ucraina 1.475
TR - Turchia 1.410
DE - Germania 1.170
VN - Vietnam 1.161
HK - Hong Kong 1.087
GB - Regno Unito 1.053
CA - Canada 794
KR - Corea 773
FR - Francia 688
FI - Finlandia 617
LU - Lussemburgo 263
BD - Bangladesh 227
IN - India 223
NL - Olanda 169
AT - Austria 159
CH - Svizzera 144
PL - Polonia 143
MX - Messico 141
JP - Giappone 130
ES - Italia 121
AR - Argentina 116
EU - Europa 108
BE - Belgio 100
ZA - Sudafrica 84
IQ - Iraq 82
GR - Grecia 66
LB - Libano 55
UZ - Uzbekistan 55
ID - Indonesia 54
PK - Pakistan 48
RO - Romania 47
VE - Venezuela 44
EC - Ecuador 40
MA - Marocco 34
CO - Colombia 33
CZ - Repubblica Ceca 33
SA - Arabia Saudita 32
LT - Lituania 29
PT - Portogallo 25
AZ - Azerbaigian 24
AU - Australia 23
EG - Egitto 23
PH - Filippine 23
AE - Emirati Arabi Uniti 22
TN - Tunisia 22
CL - Cile 21
DZ - Algeria 21
AL - Albania 18
IL - Israele 18
KE - Kenya 18
MD - Moldavia 17
JO - Giordania 16
MY - Malesia 16
NP - Nepal 15
TH - Thailandia 15
DO - Repubblica Dominicana 14
NZ - Nuova Zelanda 14
PE - Perù 14
CR - Costa Rica 12
JM - Giamaica 12
PY - Paraguay 12
UY - Uruguay 12
BG - Bulgaria 11
ET - Etiopia 10
HU - Ungheria 9
PA - Panama 9
DK - Danimarca 8
HR - Croazia 8
KZ - Kazakistan 8
OM - Oman 8
PS - Palestinian Territory 8
SY - Repubblica araba siriana 8
BY - Bielorussia 7
CI - Costa d'Avorio 7
HN - Honduras 7
SI - Slovenia 7
BO - Bolivia 6
GA - Gabon 6
GT - Guatemala 6
LK - Sri Lanka 6
LV - Lettonia 6
MN - Mongolia 6
RS - Serbia 6
SK - Slovacchia (Repubblica Slovacca) 6
SN - Senegal 6
TW - Taiwan 6
AO - Angola 5
CG - Congo 5
CY - Cipro 5
IR - Iran 5
NO - Norvegia 5
SV - El Salvador 5
Totale 72.154
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Città #
Moscow 3.604
Chandler 2.690
San Jose 2.660
Singapore 2.475
Dublin 2.400
Ashburn 2.026
Jacksonville 1.782
Scuola 1.668
Dallas 1.614
Ann Arbor 1.211
New York 1.084
Hong Kong 1.062
Wilmington 907
Boardman 872
Beijing 849
Izmir 792
Hefei 745
Saint Petersburg 729
Nanjing 632
Toronto 594
The Dalles 586
Istanbul 530
Woodbridge 513
Seoul 391
Columbus 388
Los Angeles 386
Ho Chi Minh City 347
Shanghai 341
Santa Clara 332
Princeton 330
Houston 324
Dearborn 320
Lauterbourg 311
Pisa 303
Hanoi 261
Helsinki 252
Nanchang 251
Council Bluffs 244
Ogden 236
Buffalo 213
Brooklyn 199
Milan 175
São Paulo 172
Orem 168
Luxembourg 162
Munich 149
Dong Ket 130
Kunming 125
Trieste 123
Tokyo 112
Sauris 104
Seattle 101
Tianjin 99
Warsaw 99
Brussels 98
Falls Church 97
Dudelange 90
Montreal 87
Nuremberg 87
Vienna 85
Turku 82
Chicago 81
Shenyang 79
Chennai 76
Hebei 76
Denver 74
Atlanta 73
Changsha 72
Stockholm 69
Hangzhou 68
Rome 64
Boston 63
Phoenix 63
Poplar 63
London 61
Da Nang 60
San Francisco 60
Rio de Janeiro 59
Verona 59
Johannesburg 58
Jiaxing 57
Lausanne 54
Frankfurt am Main 53
Haiphong 50
Falkenstein 48
Washington 46
Ankara 45
Manchester 44
Mumbai 44
Changchun 43
Berlin 41
Las Vegas 41
Yubileyny 41
Amsterdam 40
Guangzhou 39
Mexico City 39
Belo Horizonte 38
Jakarta 38
Orange 38
Redondo Beach 38
Totale 41.954
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Nome #
Discrimination of MSA-P and MSA-C by RT-QuIC analysis of olfactory mucosa: the first assessment of assay reproducibility between two specialized laboratories 510
Detection of prion seeding activity in the olfactory mucosa of patients with Fatal Familial Insomnia 430
alpha-Synuclein Amyloids Hijack Prion Protein to Gain Cell Entry, Facilitate Cell-to-Cell Spreading and Block Prion Replication 380
Brain aging: A Ianus-faced player between health and neurodegeneration 372
Characterization of prion protein function by focal neurite stimulation 368
Whole blood gene expression profiling in preclinical and clinical cattle infected with atypical bovine spongiform encephalopathy 339
The non-octarepeat copper binding site of the prion protein is a key regulator of prion conversion 335
Differential overexpression of SERPINA3 in human prion diseases 334
Prion protein and copper cooperatively protect neurons by modulating NMDA receptor through S-nitrosylation 330
Hemoglobin mRNA changes in the frontal cortex of patients with neurodegenerative diseases 329
Synthetic mammalian prions 327
Altered Brain Hemoglobin Gene Expression in the Frontal Cortex of Patients with Alzheimer’s and Acquired Creutzfeldt-Jakob’s Disease 320
The N Terminus of the Prion Protein Mediates Functional Interactions with the Neuronal Cell Adhesion Molecule (NCAM) Fibronectin Domain 319
A new approach to follow a single extracellular vesicle-cell interaction using optical tweezers 313
Efficient RT-QuIC seeding activity for α-synuclein in olfactory mucosa samples of patients with Parkinson's disease and multiple system atrophy 309
Synthetic prions with novel strain-specified properties 307
Structural features of human prion protein variants revealed by NMR 304
Nanoparticelle di oro rivestite con polielettroliti e loro uso come medicamento per il trattamento di malattie neurodegenerative causate da aggregati proteici 298
Gene Expression Profiling of Prion-Infected Brains: a Novel Disease Signature for Neurodegeneration in Humans 297
Synthetic prions and other human neurodegenerative proteinopathies 297
Serpin inhibitors for the treatment of prion and prion-like diseases 295
A Fluorescent Styrylquinoline with Combined Therapeutic and Diagnostic Activities against Alzheimer’s and Prion Diseases 291
A structural characterization of recombinant mouse prion protein amyloid fibers 291
The mechanisms of humic substances self-assembly with biological molecules: The case study of the prion protein 288
Cellular prion protein: Role in excitotoxicity and in metal ions homeostasis 288
Soil humic substances hinder the propagation of prions 286
A single point mutation, a way to prion disease? 283
Synthetic prions: De novo prion-infected neuronal cell lines and the generation of diverse infectious materials 283
Anti-prion activity generated by two soil compounds-Humic and fulvic acids 282
Gene expression profiling of brains from bovine spongiform encephalopathy (BSE)-infected cynomolgus macaques 280
A search for auxiliary proteins in prion replication 277
Recent Advances of Biology and Medicinal Chemistry of Prion Protein and Prions: On the Road to Therapeutics 276
Developmental prion protein expression in eutherian and methaterian mammalian central nervous system 275
NMR structure of the human prion protein with the pathological Q212P mutation: insights into inherited human prion diseases 273
Conformational properties of intrinsically disordered proteins bound to the surface of silica nanoparticles 273
Processo per la preparazione di proteine inibenti i ribosomi 271
Nucleotide sequences coding for ribosome inactivating proteins 270
Anti-GM1 IgM antibodies in motor neuron disease (MND) and other neurological diseases 270
A novel expression system for production of soluble prion proteins in E.coli 269
Anti-CD30 immunotoxins with native and recombinant dianthin 30 269
Prion protein interaction with soil humic substances: environmental implications 268
Preface 268
Effects of the pathological Q212P mutation on human prion protein non-octarepeat copper-binding site 267
NMR structure of the human prion protein Q212P mutant 265
Identification of novel fluorescent probes preventing PrPSc replication in prion diseases 265
New insights into structural determinants of prion protein folding and stability 264
Developmental influence of the cellular prion protein on the gene expression profile in mouse hippocampus 263
Whole transcriptome analysis in brains from BSE-infected macaques 263
Nanobody-stabilize the crystal structure of full-length human PrP 263
Defined α-synuclein prion-like molecular assemblies spreading in cell culture 262
NMR Structures of the Human Prion Protein with Pathological Mutations: Insights Into Molecular Basis of Prion Disease 262
Methionine oxidation in α-synuclein inhibits its propensity for ordered secondary structure 262
Early structural features in mammalian prion conformation conversion 261
A system-level approach for deciphering the transcriptional response to prion infection 261
Humic substances underlies the odds of environmental TSEs transmission 259
In Absence of the Cellular Prion Protein, Alterations in Copper Metabolism and Copper-Dependent Oxidase Activity Affect Iron Distribution 258
The role of the prion protein in the internalization of α-synuclein amyloids 258
In Vitro Aggregation Assays for the Characterization of α-synuclein Prion-Like Properties 257
Antemortem Prion Diagnostics 256
Oriented immobilization of prion protein demonstrated via precise interfacial nanostructure measurements 254
Structural Variations of Prion Proteins Caused by Mutations in Human Genome 254
Antagonistic cellular functions for prion protein and its paralog doppel. 254
Glia-to-neuron transfer of miRNAs via extracellular vesicles: a new mechanism underlying inflammation-induced synaptic alterations 254
AGFD 199 - Isolation and characterization of new anti-PrP monoclonal antibodies 254
Cloning and characterization of a gene, inducible by cytokines 253
A change in the conformation of prions accompanies the emergence of a new prion strain 253
TDP-43 real-time quaking induced conversion reaction optimization and detection of seeding activity in CSF of amyotrophic lateral sclerosis and frontotemporal dementia patients 253
Use of different RT-QuIC substrates for detecting CWD prions in the brain of Norwegian cervids 253
Aberrant ERK 1/2 complex activation and localization in scrapie-infected GT1-1 cells 251
Characterization of four new monoclonal antibodies against the distal N-terminal region of PrP(c) 251
Astrocytes-derived extracellular vesicles in motion at the neuron surface: Involvement of the prion protein 251
NMR structure of the human prion protein with the pathological Q212P mutation reveals unique structural features 250
Pin1 and neurodegeneration: a new player for prion disorders? 249
Tau-Centric Multitarget Approach for Alzheimer's Disease: Development of First-in-Class Dual Glycogen Synthase Kinase 3β and Tau-Aggregation Inhibitors 249
In silico/in vitro screening and hit evaluation identified new phenothiazine anti-prion derivatives 249
Altered molecular signaling in neuronal cell models of prion infection 248
Dominant-negative effects in prion diseases: insights from molecular dynamics simulations on mouse prion protein chimeras 247
Prions 246
Ligands binding to prion protein for use in the treatment of synucleinopathies 245
Prion and prion-like protein strains: Deciphering the molecular basis of heterogeneity in neurodegeneration 242
Opposite Structural Effects of Epigallocatechin-3-gallate and Dopamine Binding to α-Synuclein 241
Structural determinants in prion protein folding and stability 240
Structural facets of disease-linked human prion protein mutants: A molecular dynamic study 239
De novo generation of mammalian prions 238
Brain delivery of AVV9 expressing anti-PrP molecules delays prion disease onsite in mice 238
Prion protein and aging 237
Aged PrP null mice show defective processing of neuregulins in the peripheral nervous system 237
The cellular prion protein increases the uptake and toxicity of tdp-43 fibrils 237
Developmental role of the prion protein in the nervous system 236
Humic substances and uses thereof in agro-environment 236
NMR Structural Studies of Human Cellular Prion Proteins 236
Humic substances and therapeutic uses thereof 235
NMDA Receptor and L-Type Calcium Channel Modulate Prion Formation 235
A novel class of potential prion drugs: preliminary in vitro and in vivo data for multilayer coated gold nanoparticles 234
Insights into molecular structures of human prion proteins with inherited mutations by NMR 234
Toward the molecular basis of inherited prion diseases: NMR structure of the human prion protein with V210I mutation 233
Assessment of doxycycline treatment on prion deposition in the olfactory epithelium of patients with Fatal Familial Insomnia: Possible mirroring of the CNS alterations 232
Effect of extracellular vesicles derived from distinct brain cells on A beta toxicity and assembly: focus on microglia derived vesicles 232
Measuring prions causing bovine spongiform encephalopathy or chronic wasting disease by immunoassays and transgenic mice 231
Inferring prion partners from Gene-Networks 231
Totale 27.362
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Categoria #
all - tutte 267.969
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 267.969
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021521 0 0 0 0 0 0 0 0 0 0 0 521
2021/20223.292 483 370 18 334 568 94 202 365 144 107 195 412
2022/20238.209 1.218 896 735 782 431 1.663 883 528 769 62 114 128
2023/20244.799 279 71 178 82 708 1.960 184 261 739 66 59 212
2024/202516.623 2.325 800 1.519 3.663 1.677 719 799 843 660 544 1.502 1.572
2025/202623.816 986 1.971 1.668 2.404 3.453 5.121 3.966 951 1.107 1.146 643 400
Totale 73.594